21st Century Respiratory Toxicology: Complex 3-dimensional Test Systems Provide Human-relevant Data and Will Benefit from Standardization Efforts

Amanda Holdan News, Webinars

Please join us for our next webinar installment with Dr. Holger Behrsing who will provide an overview of respiratory toxicology and discuss the different types of test systems that provide more relevant data and benefits.    What you’ll learn:  Exposure to in vitro/ex vivo pulmonary models used to evaluation complex human pulmonary adverse events How 3D test systems differ and …

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Increasing Scientific Confidence in Reliable and Relevant Approaches for Regulatory Testing – A Respiratory Toxicity Case Study

Amanda Holdan Webinars

Please join Dr. Amy Clippinger and Dr. Andreas Stucki as they share their experience with New Approach Methods and regulatory testing; walking us through their case study on Respiratory Toxicity.  What you’ll learn:  To gain confidence in new approach methodologies (NAMs) for predicting human health effects, it is essential to focus on the relevance of the test system to human …

HepaRG cells

HepaRG cells: a fit-for-purpose system for hepatic modeling and DILI (Drug-Induced Liver Injury) prediction 

Amanda Holdan Webinars

In this webinar,  Pamela Bachour El Azzi, PhD discussed the different applications of HepaRG cells: induction studies, DILI (cholestasis, steatosis) and the 3D systems.What you’ll learn:  Coverage of key information about HepaRG cell model and its benefits The use of HepaRG cells for CYP induction and hepatotoxicity studies HepaRG cell engineering and modes of culture All registered participants will receive …

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New Alternative and Approach Methods to Assess Genotoxicity in Human Relevant Systems

Amanda Holdan Webinars

We just showcased our new Chief Scientific Officer, Leslie Recio, PhD, DABTin our May 10th webinar. Les discussed integrating traditional genetic toxicology endpoints with genomic profiling to assess genotoxicity in the HepaRG™ cell platform. He furthere explained how high throughput comet assay using CometChip® technology, a single cell array platform developed at MIT, flow cytometry-based micronucleus (MN) assay, and toxicogenomics …