ScitoVation is honored to work with various industry associations. We help these associations address gaps for the chemicals in their members’ portfolio or answer [research] questions from regulators and other stakeholders. We serve as a trusted provider of scientific solutions to help develop or implement a research agenda that addresses the needs of their members. Here are examples of problems we’ve solved for these clients:
- Understanding the mode of action of compounds: For the American Beverage Association (ABA), there was concern that one of the compounds widely used by the industry could cause cancer. We showed that the mode of action for the chemical was Ppar-alpha which is known to lead to cancer in animals but not humans. [Put link to paper and case study]
- Develop computing tools to rank chemicals for member companies: For an industry association [Cosmetic Europe], we developed Physiologically Based Pharmacokinetic (PBPK) models that rank chemicals based on estimated levels of internal exposure to humans. These data will help companies determine the potential risk of new compounds compared to others already on the market.
- Extrapolating data from in vitro or in vivo studies to human equivalent data: For CAPHRA (Council for the Advancement of Pyrethroid Risk Assessment), an industry association of companies in crop life that manufacture a class of compounds named as pyrethroids, we were able to show that children were not more susceptible to the compounds than adults.
Additionally, for our association clients, we’ve provided value by conducting webinars and other outreach to help implement the findings from our studies. Also, associations and their members appreciate the fact that due to our scientific credence the results are more likely to be accepted. In fact, because of our relationships with the various stakeholders in the risk assessment community, we see ourselves as a bridge between industry, academia, regulators, and non-government organizations.
We are proud to serve the following associations:
- American Chemistry Council
- American Beverage Association
- Cosmetic Europe
Case Study: Using Transcriptomics To Determine Interspecies Differences In The Mode Of Action for the American Beverage Association