DURHAM, N.C. (PRWEB) July 11, 2023: ScitoVation is the recipient of the National Institute of Environmental Health Science (NIEHS) Small Business Innovation Research (SBIR) Phase I award of $269,977. The SBIR program is a highly competitive program that encourages domestic small businesses to engage in Federal Research/Research and Development (R/R&D) with the potential for commercialization; enabling small businesses to explore …
(R)Evolution in Validation: Establishing Scientific Confidence in NAMs
Nicole Kleinstreuer, PhD, the director of the NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) and the executive director of the congressionally mandated Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM). spoke on July 18th, 2023. Dr. Kleinstreuer discussed a topic very important to our industry; a framework comprising five essential elements to establish scientific …
ScitoVation Recipient of National Institute of Environmental Health Science Small Business Innovation Research Phase II Award of $1.8 Million
DURHAM, N.C. (PRWEB) May 24, 2023 ScitoVation is the recipient of the National Institute of Environmental Health Science (NIEHS) Small Business Innovation Research (SBIR) Phase II award of $1.8 Million that is granted over two years in $900,000 increments. The SBIR program is a highly competitive program that encourages domestic small businesses to engage in Federal Research/Research and Development (R/R&D) …
A Source to Outcome Approach for Inhalation Risk Assessment: The Importance of Collaboration
Doug Wolf, DVM, PhD, discusses the creation and use of the Souce-to-Outcome framework, a new NAM incorporating a novel mathematical procedure developed to estimate the human equivalent concentration (HEC) for inhalation risk assessment based upon the relevant aerosol characterization, respiratory dosimetry modeling, and endpoints derived from an in vitro assay using human respiratory epithelial tissue. What you’ll learn: Introduction to …
NAM-Driven Computational Pipelines for Safety and Regulatory Framework
Andy Nong, PhD, ScitoVation’s Director of Computational Toxicology, is our guest speaker for this exciting webinar and new product announcement. Andy will share different computational pipelines that can complement a tier assessment approach for various forms of data such as in vitro screening tests or animal studies. What you’ll learn: How to integrate exposure and toxicity data in a quantitative …
Gene expression biomarkers as tools to interpret high-throughput transcriptomics data stream
We kicked 2023 off strong with our first webinar led by Dr. Chris Corton, Molecular Toxicologist in the Center for Computational Toxicology and Exposure at the U.S Environmental Protection Agency (EPA). Gene expression biomarkers are becoming increasingly important tools to assess mode of action (MOA), determine benchmark dose, and define point of departure for risk assessment. We welcomed Chris to …
A revolution in mutagenicity testing: exploring the utility of error-corrected next-generation sequencing to quantify and characterize mutations
The second November installment of our webinar series is with Carole Yauk, PhD, University of Ottawa took place on November 29th at 11 ET. Dr. Yauk will explored the utility of error-corrected next-generation sequencing to quantify and characterize mutations. What you’ll learn: Introduction to error-corrected next-generation sequencing (ecNGS) and its advantages over conventional approaches in chemical mutagenicity assessment; Proof of …
New Approach Methodologies for Genetic Toxicity Assessment and Regulatory Evaluation of New and Existing Substances Description
The next installment of our webinar series is with Alexandra Long, PhD, from Health Canada. Alexandra will discuss NAMs as they relate to genetic toxicity. Dr. Long will provide an overview of an integrated, multi-endpoint, higher throughput, in vitro NAM platform, termed GeneTox21, led by Health Canada scientists, for the assessment of chemically induced genetic toxicity. What you’ll learn: The value …
Andy Nong Joins ScitoVation as Director of Computational Toxicology
DURHAM, N.C. (PRWEB)July 11, 2022 ScitoVation announced today the new Director of Computational Toxicology, Andy Nong PhD, formerly Health Canada’s Acting Manager of the Exposure and Biomonitoring Division and Principal Research Scientist for the Computational Toxicology Laboratory of the Environmental Health Sciences and Research Bureau. Dr Nong has been developing toxicokinetic and biological modeling research to advance alternative risk assessment …