Artificial Intelligence (AI) is impacting all types of work, including toxicology. Dr Hartung will discuss how to move toxicology to a more holistic and integrated paradigm using AI and how AI plays a role in setting the direction of “Toxicology for the 21st Century 2.0” in future decades. What you’ll learn: Sources of Big Data for toxicology and various AI …
We just had a wonderful talk from Dr. Dan Hoer. Dr Hoer is a physical scientist with the US Environmental Protection Agency, Office of Pesticide Programs. His talk will focus on non-linear PBPK modeling, and the advantages offered by this approach. What you’ll learn: Important advantages of PBPK modeling over statistical methods that are often restricted to bimodal distinctions of …
Nicole Kleinstreuer, PhD, the director of the NTP Interagency Center for the Evaluation of Alternative Toxicological Methods (NICEATM) and the executive director of the congressionally mandated Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM). spoke on July 18th, 2023. Dr. Kleinstreuer discussed a topic very important to our industry; a framework comprising five essential elements to establish scientific …
Doug Wolf, DVM, PhD, discusses the creation and use of the Souce-to-Outcome framework, a new NAM incorporating a novel mathematical procedure developed to estimate the human equivalent concentration (HEC) for inhalation risk assessment based upon the relevant aerosol characterization, respiratory dosimetry modeling, and endpoints derived from an in vitro assay using human respiratory epithelial tissue. What you’ll learn: Introduction to …
Andy Nong, PhD, ScitoVation’s Director of Computational Toxicology, is our guest speaker for this exciting webinar and new product announcement. Andy will share different computational pipelines that can complement a tier assessment approach for various forms of data such as in vitro screening tests or animal studies. What you’ll learn: How to integrate exposure and toxicity data in a quantitative …
We kicked 2023 off strong with our first webinar led by Dr. Chris Corton, Molecular Toxicologist in the Center for Computational Toxicology and Exposure at the U.S Environmental Protection Agency (EPA). Gene expression biomarkers are becoming increasingly important tools to assess mode of action (MOA), determine benchmark dose, and define point of departure for risk assessment. We welcomed Chris to …
The second November installment of our webinar series is with Carole Yauk, PhD, University of Ottawa took place on November 29th at 11 ET. Dr. Yauk will explored the utility of error-corrected next-generation sequencing to quantify and characterize mutations. What you’ll learn: Introduction to error-corrected next-generation sequencing (ecNGS) and its advantages over conventional approaches in chemical mutagenicity assessment; Proof of …
The next installment of our webinar series is with Alexandra Long, PhD, from Health Canada. Alexandra will discuss NAMs as they relate to genetic toxicity. Dr. Long will provide an overview of an integrated, multi-endpoint, higher throughput, in vitro NAM platform, termed GeneTox21, led by Health Canada scientists, for the assessment of chemically induced genetic toxicity. What you’ll learn: The value …
Please join us for our next webinar installment with Dr. Holger Behrsing who will provide an overview of respiratory toxicology and discuss the different types of test systems that provide more relevant data and benefits. What you’ll learn: Exposure to in vitro/ex vivo pulmonary models used to evaluation complex human pulmonary adverse events How 3D test systems differ and …