Melvin E. Andersen Biomarkers of exposure can be measured at lower and lower levels due to advances in analytical chemistry. Using these highly sensitive methods, some epidemiology studies report associations between plasma and urinary biomarkers… Read more »
Better alternative models for risk assessment: In vitro inhalation toxicity assay and dosimetry modeling
Last week, my colleague, Scott Slattery, presented a webinar on in vitro inhalation point-of-contact toxicity testing with vapors. It brought me back to when I started working with Scott last year on this project. As a physiologically based pharmacokinetic modeler, the only time I worked in a lab…
Disinfecting water reduces death by killing waterborne disease. But could the disinfection process also be detrimental to our health?
Using Physiologically Based Pharmacokinetic (PBPK) Modeling and In vitro to In vivo Extrapolation (IVIVE) in Risk Assessment
By Mel Andersen, Ph.D., Senior Program Advisor It’s a grand time to be a toxicologist committed to using non-animal based biological and computational methods to assess the safety of chemicals and chemical products for human populations. My toxicology career… Read more »