Marjory Moreau1*  Liam Simms2 Melvin E. Andersen1 Edgar Trelles Sticken3 Roman Wieczorek3 Sarah Jean Pour3 Fiona Chapman2 Karin Roewer3 Sandra Otte3 Jeffrey Fisher1 Matthew Stevenson2Roman Wieczorek3 (1) ScitoVation, LLC, Research Triangle Park, NC 27713, USA (2) Imperial Brands, PLC, Bristol, United Kingdom (3) Reemtsma Cigarettenfabriken GmbH, An Imperial Brands PLC Company, Hamburg, Germany Abstract: With the use of in vitro new approach …