Information Synthesis

Information Synthesis Reports for Regulatory and Product Safety Decisions

Scientific evidence is expanding faster than most teams can evaluate it. ScitoVation helps turn fragmented literature, regulatory documents, and scientific data into clear, structured, scientist-reviewed reports.  Work that once took weeks of manual review now moves through a faster, repeatable workflow.

Our information synthesis workflows support critical reviews, scoping reviews, drug impurity assessments, post-market surveillance summaries, litigation support, and custom safety reports.

What we help you answer

• What does the current literature say about this compound, class, endpoint, or exposure scenario?
• Where is there scientific agreement, and where are there areas of disagreement?
• What are regulators, academic researchers, and other stakeholders emphasizing?
• What new evidence has emerged since the last assessment?
• Is the concern supported by human-relevant data?
• What studies would most directly reduce uncertainty?

What we deliver

• Critical reviews and scoping reviews
• Weight-of-evidence summaries
• Drug impurity safety assessments
• Post-market surveillance summaries
• Regulatory intelligence reports
• Litigation support reports
• Chemical class comparison reports
• Recurring literature updates

Workflow

1. Define the scientific question and decision context.
2. Build a structured search strategy and evidence framework.
3. Extract and organize evidence using scientist-reviewed workflows.
4. Identify areas of agreement, disagreement, and uncertainty.
5. Add mechanistic or exposure context where appropriate using transcriptomics, PBPK/qIVIVE, or other established methods.
6. Deliver a structured report with traceable sources and conclusions.