We are excited to share our next webinar speaker is Pamela Bachour El Azzi, PhD. Pamela will discuss the different applications of HepaRG cells: induction studies, DILI (cholestasis, steatosis) and the 3D systems. What you’ll learn: Coverage of key information about HepaRG cell model and its benefits The use of HepaRG cells for CYP induction and hepatotoxicity studies HepaRG cell …
We just showcased our new Chief Scientific Officer, Leslie Recio, PhD, DABTin our May 10th webinar. Les discussed integrating traditional genetic toxicology endpoints with genomic profiling to assess genotoxicity in the HepaRG™ cell platform. He furthere explained how high throughput comet assay using CometChip® technology, a single cell array platform developed at MIT, flow cytometry-based micronucleus (MN) assay, and toxicogenomics …
DURHAM, N.C. (PRWEB) APRIL 28, 2022 ScitoVation is pleased to announce Leslie Recio, PhD, DABT, as the new Chief Scientific Officer. Dr. Recio was the Chief Scientific Officer and Director of the Genetic and Molecular Toxicology group at ILS. Dr. Recio will help lead the team of Senior Scientists, drive priorities in New Approach Methods and help secure new business ventures. …
DURHAM, N.C. (PRWEB) MARCH 24, 2022 ScitoVation will release its first Annual New Approach Methods Report at Society of Toxicology 61st Annual Meeting March 27th –31st. The report features highlights from 2021 on ScitoVation’s activities including summaries of key research, projects and their value for clients and their ecosystem; the championing of new approach methods (NAMs) through blogs, webinars, and …
Posted by Dr. Mel Andersen, Senior Research Fellow, ScitoVation. ScitoVation is pleased to announce that Senior Research Fellow, Dr. Jeffrey W. Fisher (Jeff) is the recipient of the 2022 Arnold J. Lehman Award from the Society of Toxicology (SOT). SOT is a professional and scholarly organization of scientists from academic institutions, government, and industry with membership from both the …
Dr. Kannan Krishna, Chief of the Air and Site Assessment and Climate indicators Branch (ASACIB) at the Office of Environmental Health Hazard Assessment (OEHHA) of California Environmental Protection Agency, will reflect the ground-breaking work over the past 30 years in the area of chemical structure property relationships and PBPK modeling and the current thinking about way forward. What you’ll learn: …
Please join us for our next webinar on November 9 at 11am ET by Dr. Kannan Krishnan, Chief of the Air and Site Assessment and Climate indicators Branch (ASACIB) at the Office of Environmental Health Hazard Assessment (OEHHA) of California Environmental Protection Agency. He will take us through the journey of his lab’s work on chemical structure-property relationships for PBPK modeling …
Our first speaker, Stephen Ferguson, Ph.D., will discuss efforts by the Division of the National Toxicology Program (DNTP) to develop and qualify in vitro toxicology screening models using 3D spheroid cultures of human hepatocytes entitled: “High-throughput transcriptomics with physiologically-relevant in vitro models to predict human hepatotoxicity with environmental chemicals.” This presentation will be followed by a presentation from Ella Atlas, …
Conventional concepts of points of departure for adverse effects (e.g., NOAEL/LOAEL) do not translate directly to gene expression data. The benchmark dose approach offers a robust alternative method, and has been adapted to transcriptomics. Benchmark Dose is a data driven mathematical approach to determine a dose at which a significant change in response is detected. It is applicable to continuous data such as gene expression data where …