Thanks to all who attended the first presentation of the inaugural Advancement of Transcriptomics for Toxicology initiative (ATTi) series: “Advancing Transcriptomics in Safety Decision Making,” presented by Patrick McMullen, Ph.D. If you are interested in a copy of the presentation, please contact firstname.lastname@example.org.
PRESENTATION ABSTRACT: The application of transcriptomics technologies to chemical safety decision making—or toxicogenomics—has evolved as a valuable tool in toxicology. Transcriptomics identifies and measures the molecular effects that underpin physiological changes. As such, it provides mechanism-based hazard identification and dose response characterization. In the first installment of our webinar series on real-world applications of toxicogenomics, ScitoVation’s Patrick McMullen will introduce key areas of research coupling transcriptomics with in vitro and in vivo toxicological models, touching on mode-of-action principles, toxic equivalence, and biologically-based read across.