September 12, 2025
ScitoVation is the premier startup company for scientists who want to explore cutting-edge research and make a significant impact in the toxicology industry. You will be part of a highly-sought-after team of thought leaders and collaborators who are dedicated to finding innovative solutions to assess the safety of chemicals and products. Our team is driven by using the best science in chemical safety to improve risk assessment and decision making for clients. We are also at the forefront of developing next generation new approach methodologies (NAMs) and spearheading the efforts required to get key-stakeholder buy in ranging from regulatory bodies to pharma organizations. It’s an exciting time to join our organization with many companies prioritizing Next Generation Risk Assessment and few that deliver on its requirements. With a vision of being THE trusted source in chemical safety & assessment – while elevating human and environmental health and well-being, do you have what it takes to join our team and make your mark?
Job Overview:
ScitoVation is seeking a Senior Principal Scientist in PBPK/IVIVE who will serve as both a scientific leader and a business driver. Unlike traditional technical positions, this role emphasizes leveraging your reputation, scientific expertise, and professional network to generate new business opportunities, build client relationships, and expand ScitoVation’s impact in the field of computational toxicology. You will collaborate closely with our existing PBPK modeling team, who execute the technical modeling, while you focus on securing projects, shaping strategy, and ensuring scientific excellence in client-facing deliverables.
The ideal candidate is a recognized thought leader in PBPK/IVIVE, particularly in areas such as reproductive and developmental safety, with a proven ability to influence the field through publications, regulatory engagement, and conference presence. You are expected to bring in revenue by cultivating client partnerships, winning contracts, and positioning ScitoVation as the partner of choice for PBPK and NAMs.
Accountable for:
- Leading scientific strategy in PBPK/IVIVE and reproductive safety, ensuring ScitoVation remains at the forefront of NAMs.
- Driving revenue generation by leveraging your network to secure new projects, collaborations, and long-term client relationships.
- Representing ScitoVation externally through conferences, publications, and regulatory/scientific forums, reinforcing the company’s brand and thought leadership.
- Overseeing project design and ensuring scientific rigor, while delegating hands-on modeling work to ScitoVation’s existing PBPK modelers.
- Authoring and reviewing client-facing reports, technical notes, and regulatory submissions that meet the highest scientific and professional standards.
- Collaborating with toxicologists, computational scientists, and business development staff to align scientific capability with client needs.
Education and Experience:
- PhD in pharmacokinetics, chemical engineering, computational toxicology, pharmacometrics, or a related discipline.
- Established expertise and recognition in PBPK/IVIVE modeling, with a strong publication record and active participation in scientific/regulatory communities.
- Demonstrated success in generating revenue, securing grants or contracts, or building sustainable client relationships.
- Proven ability to act as a principal investigator or project leader in collaborative industry or regulatory science settings.
- Familiarity with simulation platforms (e.g., PK-Sim, GastroPlus, Berkeley Madonna, MATLAB) and their application to IVIVE and reproductive safety.
Competencies:
- Strong business development acumen and ability to translate scientific expertise into client value.
- Outstanding scientific communication and presentation skills.
- Ability to balance scientific vision with practical business goals.
- High level of independence, accountability, and motivation to grow ScitoVation’s PBPK practice.
Position Type/Expected Hours of Work:
This is a full-time position, and hours of work and days are generally Monday through Friday, 9:00 a.m. to 5 p.m. Work outside of normal hours will sometimes be required.
Travel:
Certain amount of travel is expected for conferences and scientific presentations.
Supervisory Responsibilities:
This role does not have supervisory responsibilities.
Other Duties:
Please note this job description is not designed to cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice. The base pay range will reflect the anticipated base pay for this position if a selected candidate were to be in North Carolina. Base pay may vary based on location and other factors.
Only candidates selected for an interview will be contacted.
Please submit cover letter and resume to rbarutcu@scitovation.com