Research and Publications

  • J Zhu, H Wang, F Chen, J Fu, Y Xu, Y Hou, HH Kou, C Zhai, MB Nelson, Q Zhang, ME Andersen, and J Pi. An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy. Free Radic. Biol. Med. 99 : 544-556 (Oct 12, 2016). [pubmed] [pdf]
  • Y Chen, Y Xu, H Zheng, J Fu, Y Hou, H Wang, Q Zhang, M Yamamoto, and J Pi. The role of nuclear factor E2-Related factor 2 and uncoupling protein 2 in glutathione metabolism: Evidence from an in vivo gene knockout study. Biochem. Biophys. Res. Commun. 478 (1) : 87-92 (Sep 9, 2016). [pubmed] [pdf]
  • H Peng, H Wang, P Xue, Y Hou, J Dong, T Zhou, W Qu, S Peng, J Li, PL Carmichael, B Nelson, R Clewell, Q Zhang, ME Andersen, and J Pi. Suppression of NRF2-ARE activity sensitizes chemotherapeutic agent-induced cytotoxicity in human acute monocytic leukemia cells. Toxicol. Appl. Pharmacol. 292 : 1-7 (Feb 1, 2016). [pubmed] [pdf]
  • Q Zhang, S Bhattacharya, J Pi, RA Clewell, PL Carmichael, and ME Andersen. Adaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety Assessment. Toxicol. Sci. 147 (2) : 302-16 (Oct 1, 2015). [pubmed] [upload pdf] -->
  • Y Adeleye, M Andersen, R Clewell, M Davies, M Dent, S Edwards, P Fowler, S Malcomber, B Nicol, A Scott, S Scott, B Sun, C Westmoreland, A White, Q Zhang, and PL Carmichael. Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment. Toxicology 332 : 102-11 (Jun 5, 2015). [pubmed] [pdf]
  • J Fu, H Zheng, H Wang, B Yang, R Zhao, C Lu, Z Liu, Y Hou, Y Xu, Q Zhang, W Qu, and J Pi. Protective Role of Nuclear Factor E2-Related Factor 2 against Acute Oxidative Stress-Induced Pancreatic ? -Cell Damage. Oxid Med Cell Longev 2015 : 639191 (Apr 9, 2015). [pubmed] [pdf]
  • Q Zhang, S Bhattacharya, RB Conolly, HJ Clewell, NE Kaminski, and ME Andersen. Molecular signaling network motifs provide a mechanistic basis for cellular threshold responses. Environ. Health Perspect. 122 (12) : 1261-70 (Dec 12, 2014). [pubmed] [pdf]
  • S Bhattacharya, LK Shoda, Q Zhang, CG Woods, BA Howell, SQ Siler, JL Woodhead, Y Yang, PB Watkins, ME Andersen, and PD McMullen. Modeling drug- and chemical-induced hepatotoxicity with systems biology approaches. Front Physiol 3 : 462 (Dec 14, 2012). [pubmed] [pdf]
  • Q Zhang, J Pi, CG Woods, AM Jarabek, HJ Clewell, and ME Andersen. Hormesis and adaptive cellular control systems. Dose Response 6 (2) : 196-208 (Mar 19, 2008). [pubmed] [pdf]
  • L Li, ME Andersen, S Heber, and Q Zhang. Non-monotonic dose-response relationship in steroid hormone receptor-mediated gene expression. J. Mol. Endocrinol. 38 (5) : 569-85 (May 1, 2007). [pubmed] [pdf]