Research and Publications

  • H Wu, M Yoon, MA Verner, J Xue, M Luo, ME Andersen, MP Longnecker, and HJ Clewell. Can the observed association between serum perfluoroalkyl substances and delayed menarche be explained on the basis of puberty-related changes in physiology and pharmacokinetics? Environ Int 82 : 61-8 (Sep 29, 2015). [pubmed] [pdf]
  • J Lu, S Einhorn, L Venkatarangan, M Miller, DA Mann, PB Watkins, and E LeCluyse. Morphological and Functional Characterization and Assessment of iPSC-Derived Hepatocytes for In Vitro Toxicity Testing. Toxicol. Sci. 147 (1) : 39-54 (Sep 18, 2015). [pubmed] [pdf]
  • JF Wambaugh, BA Wetmore, R Pearce, C Strope, R Goldsmith, JP Sluka, A Sedykh, A Tropsha, S Bosgra, I Shah, R Judson, RS Thomas, and RW Setzer. Toxicokinetic Triage for Environmental Chemicals. Toxicol. Sci. 147 (1) : 55-67 (Sep 16, 2015). [pubmed] [pdf]
  • N Burden, F Sewell, ME Andersen, A Boobis, JK Chipman, MT Cronin, TH Hutchinson, I Kimber, and M Whelan. Adverse Outcome Pathways can drive non-animal approaches for safety assessment. J Appl Toxicol 35 (9) : 971-5 (Sep 5, 2015). [pubmed] [pdf]
  • OJ Trask, and PA Johnston. Standardization of high content imaging and informatics. Assay Drug Dev Technol 13 (7) : 341-6 (Sep 1, 2015). [pubmed] [upload pdf] -->
  • JD Olie, JG Bessems, HJ Clewell, J Meulenbelt, and CC Hunault. Evaluation of semi-generic PBTK modeling for emergency risk assessment after acute inhalation exposure to volatile hazardous chemicals. Chemosphere 132 : 47-55 (Aug 17, 2015). [pubmed] [pdf]
  • J Campbell, C Van Landingham, S Crowell, R Gentry, D Kaden, S Fiebelkorn, A Loccisano, and H Clewell. A preliminary regional PBPK model of lung metabolism for improving species dependent descriptions of 1,3-butadiene and its metabolites. Chem. Biol. Interact. 238 : 102-10 (Aug 5, 2015). [pubmed] [pdf]
  • AY Efremenko, J Seagrave, HJ Clewell, C Van Landingham, PR Gentry, and JW Yager. Evaluation of gene expression changes in human primary lung epithelial cells following 24-hr exposures to inorganic arsenic and its methylated metabolites and to arsenic trioxide. Environ. Mol. Mutagen. 56 (5) : 477-90 (Jun 14, 2015). [pubmed] [pdf]
  • Y Yang, S Nadanaciva, Y Will, JL Woodhead, BA Howell, PB Watkins, and SQ Siler. MITOsym®: A Mechanistic, Mathematical Model of Hepatocellular Respiration and Bioenergetics. Pharm. Res. 32 (6) : 1975-92 (Jun 12, 2015). [pubmed] [pdf]
  • Y Adeleye, M Andersen, R Clewell, M Davies, M Dent, S Edwards, P Fowler, S Malcomber, B Nicol, A Scott, S Scott, B Sun, C Westmoreland, A White, Q Zhang, and PL Carmichael. Implementing Toxicity Testing in the 21st Century (TT21C): Making safety decisions using toxicity pathways, and progress in a prototype risk assessment. Toxicology 332 : 102-11 (Jun 5, 2015). [pubmed] [pdf]