In this course, you will learn to apply an effective computational tool — physiologically based pharmacokinetic (PBPK) modeling — to translate the results of in vitro toxicity assays into estimates of safe human exposure. This one-week course will cover the principles of PBPK modeling and the application of this technique for in vitro to in vivo extrapolation (IVIVE) to support risk assessments based on non-animal methods. The course features comprehensive lectures and extensive hands-on computer modeling practice. This course will prepare you to use state-of-the-art modeling & simulation techniques to assist in estimating acceptable human exposure guidelines from the results of in vitro toxicity assays.
WHO SHOULD ATTEND?
Industrial, pharmaceutical and regulatory scientists desiring to interpret the results of in vitro toxicity assays in terms of their implications for human health
Toxicologists and research scientists who develop or conduct in vitro toxicity assays
Individuals desiring to learn how to develop and apply PBPK models
Individuals interested in promoting the use of alternatives to live animal testing for regulatory requirements such as REACH
Comprehensive take-home course materials
Breakfast and Lunch daily
Certificate of Attendance
*Students will be required to bring a PC laptop computer to the course each day for hands-on modeling exercises.
Contact Jessica Brown with questions at email@example.com