Research and Publications

  • B Foley, DL Doheny, MB Black, SN Pendse, BA Wetmore, RA Clewell, ME Andersen, and C Deisenroth. Editor's Highlight: Screening ToxCast Prioritized Chemicals for PPARG Function in a Human Adipose-Derived Stem Cell Model of Adipogenesis. Toxicol. Sci. 155 (1) : 85-100 (Jan 23, 2017). [pubmed] [pdf]
  • MM Miller, RA Alyea, C LeSommer, DL Doheny, SM Rowley, KM Childs, P Balbuena, SM Ross, J Dong, B Sun, MA Andersen, and RA Clewell. Editor's Highlight: Development of an In vitro Assay Measuring Uterine-Specific Estrogenic Responses for Use in Chemical Safety Assessment. Toxicol. Sci. 154 (1) : 162-173 (Nov 7, 2016). [pubmed] [pdf]
  • RA Clewell, and ME Andersen. Approaches for characterizing threshold dose-response relationships for DNA-damage pathways involved in carcinogenicity in vivo and micronuclei formation in vitro. Mutagenesis 31 (3) : 333-40 (May 4, 2016). [pubmed] [pdf]
  • RA Clewell, PD McMullen, Y Adeleye, PL Carmichael, and ME Andersen. Pathway Based Toxicology and Fit-for-Purpose Assays. Adv. Exp. Med. Biol. 856 : 205-230 (Jan 1, 2016). [pubmed] [pdf]
  • J Klapacz, LH Pottenger, BP Engelward, CD Heinen, GE Johnson, RA Clewell, PL Carmichael, Y Adeleye, and ME Andersen. Contributions of DNA repair and damage response pathways to the non-linear genotoxic responses of alkylating agents. Mutat Res Rev Mutat Res 767 : 77-91 (Dec 2, 2015). [pubmed] [upload pdf] -->
  • Q Zhang, S Bhattacharya, J Pi, RA Clewell, PL Carmichael, and ME Andersen. Adaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety Assessment. Toxicol. Sci. 147 (2) : 302-16 (Oct 1, 2015). [pubmed] [upload pdf] -->
  • RA Clewell, JJ Kremer, CC Williams, JL Campbell, ME Andersen, and SJ Borghoff. Tissue exposures to free and glucuronidated monobutylyphthalate in the pregnant and fetal rat following exposure to di-n-butylphthalate: evaluation with a PBPK model. Toxicol. Sci. 103 (2) : 241-59 (Jun 15, 2008). [pubmed] [pdf]
  • RA Clewell, EA Merrill, JM Gearhart, PJ Robinson, TR Sterner, DR Mattie, and HJ Clewell. Perchlorate and radioiodide kinetics across life stages in the human: using PBPK models to predict dosimetry and thyroid inhibition and sensitive subpopulations based on developmental stage. J. Toxicol. Environ. Health Part A 70 (5) : 408-28 (Mar 1, 2007). [pubmed] [pdf]