Research and Publications

  • JC van Eijkeren, JD Olie, SM Bradberry, JA Vale, I de Vries, HJ Clewell, J Meulenbelt, and CC Hunault. Modeling the effect of succimer (DMSA; dimercaptosuccinic acid) chelation therapy in patients poisoned by lead. Clin Toxicol (Phila) 55 (2) : 133-141 (Feb 5, 2017). [pubmed] [pdf]
  • SP Ramoju, DR Mattison, B Milton, D McGough, N Shilnikova, HJ Clewell, M Yoon, MD Taylor, D Krewski, and ME Andersen. The application of PBPK models in estimating human brain tissue manganese concentrations. Neurotoxicology (Dec 15, 2016). [pubmed] [pdf]
  • CD Ruark, G Song, M Yoon, MA Verner, ME Andersen, HJ Clewell, and MP Longnecker. Quantitative bias analysis for epidemiological associations of perfluoroalkyl substance serum concentrations and early onset of menopause. Environ Int (Dec 5, 2016). [pubmed] [pdf]
  • G Song, CR Peeples, M Yoon, H Wu, MA Verner, ME Andersen, HJ Clewell, and MP Longnecker. Pharmacokinetic bias analysis of the epidemiological associations between serum polybrominated diphenyl ether (BDE-47) and timing of menarche. Environ. Res. 150 : 541-8 (Oct 16, 2016). [pubmed] [pdf]
  • JM Pedersen, YS Shim, V Hans, MB Phillips, JM Macdonald, G Walker, ME Andersen, HJ Clewell, and M Yoon. Fluid Dynamic Modeling to Support the Development of Flow-Based Hepatocyte Culture Systems for Metabolism Studies. Front Bioeng Biotechnol 4 : 72 (Sep 30, 2016). [pubmed] [pdf]
  • JL Campbell, ME Andersen, PM Hinderliter, KD Yi, TP Pastoor, CB Breckenridge, and HJ Clewell. PBPK Model for Atrazine and Its Chlorotriazine Metabolites in Rat and Human. Toxicol. Sci. 150 (2) : 441-53 (Apr 21, 2016). [pubmed] [pdf]
  • CB Breckenridge, JL Campbell, HJ Clewell, ME Andersen, C Valdez-Flores, and RL Sielken. PBPK-Based Probabilistic Risk Assessment for Total Chlorotriazines in Drinking Water. Toxicol. Sci. 150 (2) : 269-82 (Apr 21, 2016). [pubmed] [pdf]
  • TS McMullin, Y Yang, J Campbell, HJ Clewell, K Plotzke, and ME Andersen. Development of an integrated multi-species and multi-dose route PBPK model for volatile methyl siloxanes - D4 and D5. Regul. Toxicol. Pharmacol. 74 Suppl : S1-13 (Feb 23, 2016). [pubmed] [pdf]
  • M Yoon, and HJ Clewell. Addressing Early Life Sensitivity Using Physiologically Based Pharmacokinetic Modeling and In Vitro to In Vivo Extrapolation. Toxicol Res 32 (1) : 15-20 (Jan 31, 2016). [pubmed] [pdf]
  • BA Wetmore, JF Wambaugh, B Allen, SS Ferguson, MA Sochaski, RW Setzer, KA Houck, CL Strope, K Cantwell, RS Judson, E LeCluyse, HJ Clewell, RS Thomas, and ME Andersen. Incorporating High-Throughput Exposure Predictions With Dosimetry-Adjusted In Vitro Bioactivity to Inform Chemical Toxicity Testing. Toxicol. Sci. 148 (1) : 121-36 (Nov 6, 2015). [pubmed] [upload pdf] -->